Non-canonical Base Pair Database | Individual Record Page 1440

Fox Lab

Department of Biology and Biochemistry | University of Houston

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- Structures of Base Pairs, Base Triples and Base Quadruples.

- "Database of non-canonical base pairs found in known RNA structures" [PDF format. Nucleic Acid Research, 2000 Jan 1; 28(1):375-376].

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NON-CANONICAL BASE PAIR DATABASE : Individual Record Page 1440

Authors: Yaremchuk A, Tukalo M, Grotli M, Cusack S

Citation: A succession of substrate induced conformational changes ensures the amino acid specificity of Thermus thermophilus prolyl-tRNA synthetase: comparison with histidyl-tRNA synthetase J Mol Biol 309(4):989-1002 June 15, 2001  [PDB link]

Base Pair Type: AU reverse Hoogsteen

Base Pair Category: Normal Purine-Pyrimidine Base Pairs; Trans Hoogsteen/Shallow groove

Sequence Context: 5'  3'
C A,*
A-U
G G,*
3'  5'

Structure: Prolyl-tRNA Synthetase form Thermus Thermophilus

Pucker Info: All C3' endo

Melting Point: *

Free Energy: *

Chemical Shift: *

Glycosidic Conf: All anti

Extra Info: A14.U8 form a mismatch

Figure: AU reverse Hoogsteen